Field effect control of translocation dynamics in surround-gate nanopores

Abstract Controlling the fast electrophoresis of nano-objects in solid-state nanopores is a critical issue for achieving electrical analysis single-particles by ionic current. In particular, it crucial to slow-down translocation dynamics nanoparticles. We herein report that focused electric field and associated water flow surround-gate nanopore can be used trap manipulate nanoscale object. fine-control electroosmosis-induced modulating wall surface potential via gate voltage. find nanoparticle captured vicinity conduit balancing counteracting electrophoretic hydrodynamic drag forces. By creating subtle force imbalance, addition, we also demonstrate gate-controllable motion moving at an extremely slow speed several tens nanometers per second. The present method may useful single-molecule detection nanochannels.